Cell Biology (Junior Research Group)
Karl-von-Frisch Straße 8, 35032 Marburg
+49-6421 28 21509
The Moog lab studies the cell biology, protein targeting mechanisms and subcellular metabolic compartmentalization of eukaryotic microalgae. Moreover, we are exploring the biotechnological potential of single-celled marine and fresh water algae as model systems for recombinant protein expression and metabolic engineering. The lab is interested in three main topics: (i) peroxisomes and the evolution of compartmentalization in complex microbial eukaryotes, (ii) the targeting of tail-anchored proteins in chromalveolates and (iii) the biological degradation of plastics using microalgae. To address these research areas, we are using classical as well as sophisticated cell biological methods, synthetic biology and bioinformatics.
algal cell biology
genomics and transcriptomics
1. Moog D, Schmitt J, Senger J, Zarzycki J, Rexer KH, Linne U, Erb TJ and Maier UG (2019) Using a marine microalga as a chassis for polyethylene terephthalate (PET) degradation. Microb Cell Fact 18:171.
2. Mix AK, Cenci U, Heimerl T, Marter P, Wirkner ML, Moog D (2018) Identification and localization of peroxisomal biogenesis proteins indicates the presence of peroxisomes in the cryptophyte Guillardia theta and other "chromalveolates". Genome Biol Evol 10:2834-2852.
3. Moog D, Przyborski JM, Maier UG (2017) Genomic and proteomic evidence for the presence of a peroxisome in the apicomplexan parasite Toxoplasma gondii and other Coccidia. Genome Biol Evol 9:3108-3121.