February 2017: Review article out
Transporters, in addition to their essential roles in nutrient uptake and extrusion of toxic compounds, can have secondary functions as sensors and information processors in bacterial signalling pathways. Together with Susanne Gebhard from the University of Bath, we here review recent advances in our understanding of such pathways and discuss the dynamic behavior of hallmark examples. We highlight how such a strategy enables the cell to integrate information about its external conditions with its current physiological state. Read more here: Piepenbreier et al., Mol. Microbiol., accepted
 

 

November 2016: New PhD student arrived

It is a pleasure to welcome Delia Casas Pastor from Spain as a new PhD student to our lab! Delia has a background in Biotechnology and received her Bachelor from the University of Salamanca in Spain. Subsquently, she received excellent training in bioinformatics and modeling approaches during her Masters' studies of Synthetic Biology at Newcastle University in the UK, and is now ready to dive into the Synthetic Biology of ECF sigma factors. Welcome Delia!

 

 

September 2016: New Master student started

We are happy that Angelika Diehl chose our lab to work on her Master thesis in the upcoming months. Angelika is a biologist and very eager to expand her skillset by computational approaches, which she will use to study the interaction between ECF sigma factors and anti-sigma factors in closer detail. Welcome Angelika!

 

 

August 2016: Welcome Andre

We warmly welcome Andre Sim from Messey University in New Zealand as a new PhD student to our lab! In his research Andre will focus on how the synthesis of the cell wall is coordinated with the global growth physiology of Bacillus subtilis.

 

 

 
July 2016: Our new lab is now ready to go

With a number of new students joining our group it was about time to move into a bigger lab that provides our wet-lab team with sufficient space. Thanks to SYNMIKRO for equipping the lab!

  

 

June 2016: New ERASMUS student arrived

We are happy to welcome Julia Manning from the University of Bath (UK) to our group! Julia studies Biochemistry and decided to join us for one year as a placement student. Her work on a quick and flexible toolkit for chromosomal integration of regulatory circuits in B. subtilis will be supported by the ERASMUS programme. 

 

 

 

June 2016: Review article published

The focus of this review is the cell envelope stress response (CESR) of B. subtilis, and in particular the response to bacitracin challenge, which is now a well-studied case that serves as a paradigm. We take an “historical” point of view, which allows the reader to follow the development of the field, from a descriptive beginning, to a better and better understanding of the mechanisms, including the latest results from our labs. Read more here: Radeck et al., Curr. Genet., online first

 

 

 May 2016: Yet another PhD scholarship

Hannah just received an acceptance letter for a scholarship via the Cusanuswerk, which will fund her PhD studies on computational modelling of antibiotic resistance modules over the next 3 years - Congratulations Hannah!!!

 



May 2016: PhD scholarship awarded

In this year's selection symposium of the IMPRS-Mic graduate school we had a number of strong candidates and we are glad that one of the IMPRS-Mic scholarships went to Andre Sim from Messey University (New Zealand). Andre chose our lab as his place to be for his PhD studies and we are looking very much forward to having him here in Marburg from August onwards!

 

April 2016: Luis joins the lab

We are happy that Luis Oviedo from Sevilla (Spain) joins our lab as a research assistant! He will work on the development of a bioinformatic database and a corresponding web-interface to it. So welcome Luis! 

 

 

 

March 2016: Paper accepted

Hooray - our next paper on the `Anatomy of the bacitracin resistance network in Bacillus subtilis' was accepted in Molecular Microbiology. In this piece we show that the resistance network against the antimicrobial peptide bacitracin is composed of multiple modules that feature active redundancy - a regulation strategy that activates the expression of additional protective layers only if other resistance modules fail. Check out the full story in Radeck et al.Mol. Microbiol. 100, 607-620.

 

 

February 2016: Paper accepted & on the cover

Our paper on `Single-cell characterization of metabolic switching in the sugar phosphotransferase system (PTS) of Escherichia coli' was accepted and finally made it to the cover of Molecular Microbiology. Using a combination of experiment and theory we show in this paper that PTS sugar utilization involves not only switching between the sugars utilized but also switching between different utilization strategies. Find out more in Westermayer et al.Mol. Microbiol. 100, 472-485.

 

SYNMIKRO Young Researchers Groups

Almost all scientific members of SYNMIKRO are actively involved in DFG’s Collaborative Research Centers (Sonderforschungsbereiche), Research Training Groups (Graduiertenkollegs), or other Cooperative Research projects. Alongside performing adventurous experiments, and reporting excellent science, SYNMIKRO substantially promotes potential Young Research Group Leaders by constantly keeping its doors open to welcome and support Young Researchers planning to set up an Independent Research Group.
Our Young Research Groups