Research

SYNMIKRO Research Program

The aim of research at SYNMIKRO is understanding molecular, biochemical, cellular, genetical, and ecological functions in microorganisms followed by construction of synthetic microbial units.

Analyses of components and functions of microbial cells are still statically determined rather than trying to study the broad molecular networking inside of living entities. Using both synthetic, analytical, and modeling approaches, SYNMIKRO aims to understand the very basics of molecular interactions leading to the sophisticated and intriguing principles of inheritance, cell division, metabolism, adaptation, and finally: evolution. The collaboration of biologists, biochemists and chemists, physicists and mathematicians, computational biologists and ethicists of SYNMIKRO offers many opportunities to tailor the capacity of microorganisms improving, or finding new playgounds, of potential application.

SYNMIKRO is divided into six research areas: Cellular Signal Processing and Regulation, Metabolism, Cellular Organisation, Chassis and Genomes, Microbial Communities, and Modeling & Bioethics. Within these six areas, a growing number of individual research projects will facilitate arriving the terra incognita of microbial life and its ever lasting capacity to colonize even the adversest locations on earth.

 

Cellular Signal Processing and Regulation

Exploring and applying signaling compounds: the oldest colloquies of the world executed in new synthetic systems.

Cellular Organization

Studying temporally and spatially controlled molecular interactions to understand and optimize cell cycle, cellular differentiation, and multicellular aggregates.

Chassis and Genomes

Scrutinizing microbial adaptations to eukaryotic hosts and determining substantial criteria for the design of minimal genomes to understand the minimum criteria of life.

Metabolism

Observing a nearly unlimited biosynthetic diversity and capacity to be exploited through combination and new design of individual enzymes.

Microbial Communities

Producing and studying synthetic microbial communities to be compared to natural communities.

Modeling and Bioethics

Applying bioinformatic tools and algorithms. Evaluation of the momentum of synthetic biology to the society.

Junior Research Groups

SYNMIKRO promotes potential Young Research Group Leaders by constantly keeping its doors open to welcome and support Young Researchers planning to set up an Independent Research Group.

SYNMIKRO Young Researchers Groups

Almost all scientific members of SYNMIKRO are actively involved in DFG’s Collaborative Research Centers (Sonderforschungsbereiche), Research Training Groups (Graduiertenkollegs), or other Cooperative Research projects. Alongside performing adventurous experiments, and reporting excellent science, SYNMIKRO substantially promotes potential Young Research Group Leaders by constantly keeping its doors open to welcome and support Young Researchers planning to set up an Independent Research Group.
Our Young Research Groups