LOEWE Center for Synthetic Microbiology
Hans-Meerwein-Straße 6, 35032 Marburg
+49-6421 28 24451
Synthetic microbiology strives for the synthesis of new functional units, their combination and integration into a cell to generate microorganisms with new characteristics and application potential. Implementation and control of synthetic pathways in a cell require a comprehensive understanding of the cellular regulatory network. Our research aims at a system-level understanding of natural occurring intra- and intercellular regulatory pathways to unravel design principles.
Comparative genomics approaches are vital towards a predictive understanding how similar genes interact to form regulatory networks in different organisms. We apply synthetic biology concepts to reprogram natural or to engineer novel regulatory modules in bacteria.
We investigate the molecular aspects of symbiotic and pathogenic plant-microbe interactions as model systems. Another focus of our work is the development of tools and methods to support automated combinatorial experiments in engineering and testing of parts, devices and modules.